Summer Studentships Funded 2023
| STUDENT | SUPERVISOR | PROJECT TITLE |
| Eugenia Barros | Laura Machesky, University of Cambridge | Macropinocytosis fueling tumour growth and invasion |
| Luna Nordenstrom | Sebastian Timmler, University of Cambridge | Studying neuron-specific myelin patterns using light microscopy |
| Deborah Martinuzzi | Pier Paolo D’Avino, University of Cambridge | Analysis of the Dynamics and Roles of Protein Phosphatase 1 β Catalytic Subunit During Mitosis Using the Auxin-Inducible Degron System and Time-Lapse Imaging |
| Isabelle Heys | David Elliott, Newcastle University | How do hormones regulate the epithelial splicing protein ESRP1 in breast cancer cells? |
| Anna Ivanova | Paul Jarvis, University of Oxford | Enhancing photosynthesis by fine tuning the chloroplast protein import machinery |
| Chai Plaza | Stuart Jenkins, Keele University | Tuning biophysical stimuli for “electroimplants†to optimise neural stem cell regenerative responses for neurological repair |
| Molly Green | Helen Weavers, University of Bristol | Exploring the Cellular Mechanisms Driving Tissue Repair Using in Vivo Drosophila Models |
| Nimrah Javaid | Dhanya Cheerambathur, University of Edinburgh | Elucidating the mechanism of action of kinetochore protein KNL-1 in dendrite branching. |
| Nial O’Reilly | Elaine Dunleavy, University of Galway | Investigating centromere dynamics during spermiogenesis in Drosophila melanogaster males. |
| Sarah Bristow | Martin Lowe, University of Manchester | Exploring the diversity of cargo traffic in the secretory pathway |
| Gabriela Marinescu | Harry Mellor, University of Bristol | The polarized transport of fatty acids across the endothelium |
| Matthew Gray | Andrew Fielding, Lancaster University | Understanding the role of the centrosome clustering protein KIFC1 in cancer and normal cells: integrated analysis of mitosis, cell cycle, migration and survival. |
| Joel Makopa Malungu | James Pritchett, Manchester Metropolitan University | Investigating PDLIM protein function in hepatic stellate cells |
Summer Studentships Funded 2022
| STUDENT | SUPERVISOR | PROJECT TITLE |
| Courtney Townend | Joe CostelloUniversity of Exeter | Are all VAPs equal? A study on the ALS-linked mutations of VAP proteins |
| Isobel Diaz | Michael Clague, University of Liverpool | Investigating the interplay between USP9X and the turnover of centriolar satellites |
| Rhiannon Hughes | Girish Ram Mali, University of Bristol | Cellular studies on Shulin/DNAAF9 – a novel dynein assembly factor |
| Ameena Naji | Michelle Peckham, University of Leeds | Structure and regulation of Myosin 10: a filopodial motor protein |
| Sneha Sara Binu | Helen Foster, University of Hertfordshire | Therapy induced senescence in liquid biopsies. Could markers of senescence be used to predict chemo-resistance and cancer re-emergence? |
| Georgia Boothe | Katrin Deinhardt, University of Southampton | Investigating mechanisms of synaptic protein homoestasis – what ubiquitinates SNAP-25? |
| Danielle Harte | Jeremy Simpson, University College Dublin | Systematic high-content survey of Rab GTPase function in a 3D spheroid model |
| India Oxley | Elizabeth Smythe, University of Sheffield | Investigation of Fbxw10, a novel regulator of macropinocytosis |
| Phineas Smith | Bernadette Carroll, University of Bristol | Exploring the role of mTORC1 signalling in Purkinje cell development |
| Ece Urani | Giampietro Schiavo, University College London | Investigation of the function of a new genetic network connecting risk for Alzheimer’s disease and severe COVID-19 in human myeloid cells |
| Lizzie Ruddell | Martin Goldberg, Durham University | Novel approaches to stiffen nuclei to prevent cell invasion |
| Joel Baby | Alice Pollitt, University of Reading | Investigating the fate of receptor-ligand interactions at the platelet synapse |
Summer Studentships Funded 2021
| STUDENT | SUPERVISOR | PROJECT TITLE |
|
Sakina Amin |
Mark Morgan, University of Liverpool |
Targeting metastasis: The role of Integrin-HER2 crosstalk in breast cancer brain metastases |
|
Dai Nakamura |
Anthony Roberts, Birkbeck, University of London |
Purification of mammalian intraflagellar transport complexes |
|
Kathryn Brooks |
Jordan Raff, University of Oxford |
Analysis of centrosome growth dynamics |
|
Menan Loganathan |
Ewa Paluch, University of Cambridge |
Biochemical and biophysical characterisation of the migration of mammalian primordial germ cells |
|
Samuel Skoda |
Kristina Kirschner, University of Glasgow |
Examining DNA methylation dynamics throughout human lifetime by constructing an old-age epigenetic clock |
|
Abigail Smith |
Frances Brodsky, University College London |
Investigating GLUT4 trafficking pathway regulation by the clathrin variant CHC22 in HeLa and human muscle cells |
|
Ilona Willson |
Jason King, University of Sheffield |
Picking apart PIKfyve: Dissecting how the PIKfyve Protein Regulates Phagosome Maturation |
|
Molly Martin |
Jonathon Pines, Institute of Cancer Research |
Using CRISPR-Cas9 to generate an APC8-NFAST cell line |
|
Harry Moxom |
Paul Pryor, University of York |
The role of Mon1b in regulating lysosome biogenesis |
|
Magdalena Smolkova |
Stefan Marciniak, Cambridge Institute for Medical Research |
The effect of polymerogenic Z α1-antitrypsin on the mobility of ERp18 chaperone |
|
Nicole Acuti |
Lovorka Stojic, Barts Cancer Institute, Queen Mary University of London |
RNA-mediated regulation of cell division |
|
Tristan Copping |
Ian Gibbs-Seymour, Department of Biochemistry, University of Oxford |
Decoding ubiquitin signalling at DNA replication-coupled lesions |
Summer Studentships Funded 2020
| STUDENT | SUPERVISOR | PROJECT TITLE |
|
Melinda Van Kerckvoorde |
Pleasantine Mill, MRC HGU, University of Edinburgh |
Exploring how the propensity of primary cilia to function as signalling organelles varies with the cell cycle |
|
Maria Carreira |
Elina Vladimirou, UCL, Cancer Institute |
Investigating the role of PI3K signalling on microtubule and chromosome dynamics |
|
Emily Edwards |
Judy Coulson, University of Liverpool |
Identifying DUB regulators of TEADs, the YAP/TAZ effectors in the Hippo signalling pathway |
|
Anna Rooth |
Harry Mellor, University of Bristol |
The role of endothelial secretion in vascular disease |
|
István Darabán |
Alessio Vagnoni, King’s College London |
Mitochondrial trafficking and function in ageing dorsal root ganglion neurons |
|
Megan Ferguson |
Luke Chamberlain, University of Strathclyde |
Analysis of the mechanisms regulating intracellular targeting of the tumour suppressor Sprouty-2 |
|
Megan Hardy |
Marisa Segal, University of Cambridge |
Ras inhibition by a novel class of Ras-interacting proteins – a synthetic approach |
|
Kathiravan Mohan |
Tom Nightingale, QMUL |
Motor control of regulated VWF secretion |
|
Andrea Armero Mateu |
Amanda Coutts, Nottingham Trent University |
Regulation of p53 during autophagy in human cancer |
|
David Lingard |
Kathy Niakan, Francis Crick Institute |
An interactive web resource of gene expression in the human pre-implantation embryo Identifying new regulators of mTORC1 signalling |
|
Vivian Montesano |
Yolanda Calle, University of Roehampton |
Role of WIP in multiple myeloma (MM) migration and resistance to therapy |
|
Anna Maria Zhivotikova |
Joe Costello, University of Exeter |
Hijacking of membrane contact sites by intracellular pathogens |
Summer Studentships Funded 2019
| STUDENT | SUPERVISOR | PROJECT TITLE |
| Yangye Zhang | Jeremy Green, Kings College London | Analysis of cell adhesion and cytoskeletal proteins involved in vertical cell migration during ectodermal placode invagination |
| Yaiza Arranz Martínez | Paul Pryor, University of York | The role of Synaptogyrin-2 in regulating the insulin-responsive glucose transporter GLUT4 |
| Rachel Finlay | Sophie Acton, LMCB, University College London | Identifying the role of macrophages in maintaining lymph node integrity |
| Liza Zhabina | Simon Cook, Babraham Research Campus, Cambridge | Characterising the Regulatory Mechanisms on ERK5 in Naïve and Primed ES cells |
| Ana Raffaelli | Nathan W. Goehring, The Francis Crick Institute | Exploring state changes in polarity protein PAR-2 via single particle tracking / modelling |
| Junliang Lin | Mark R. Morgan, University of Liverpool | Investigating the potential risks of therapies based on umbilical cord-derived mesenchymal stromal cells |
| Samia Mohammed | Anne Straube, University of Warwick | Cooperation of molecular motors and passive crosslinkers |
| Karolina Jagielka | Francisco Rivero, University of Hull | Dissecting the role of the neuropeptide CGRP in regulating human lymphatic endothelial cell monolayer permeability and the cytoskeleton |
| Riya Vekaria | Elisabeth Ehler, King’s College London | Beta-Adrenergic Signalling and Intercalated Disc Composition |
| Adam Wells | Martin W. Goldberg, Durham University | Investigating nucleoporin Nup358 association with microtubules using multiple and correlative high-resolution microscopy techniques |
| Krystyna Sadzikowska | Ewa Paluch, University of Cambridge | Investigating the molecular control of cell shape changes in mouse embryonic stem cells exiting naive pluripotency |
| Jessicca Lines | Carine De Marcos Lousa | Expression of Human Clathrin Heavy chains in a Plant model T. Benthamiana |
Summer Studentships Funded 2018
| STUDENT | SUPERVISOR | PROJECT TITLE |
| Sophie Alice Twigger | Alistair Hume | The role of actin nucleation and assembly proteins (ANAPs) in myosin-Va dependent organelle transport |
| Jeremie Subrini | Kathy Niakan | Engineering human embryonic stem cells to investigate the function of SMAD2 and SMAD3 signalling in pluripotency |
| Shawn Cottrill | Sonia Rocha | Role of KDM5 family members in the control of histone methylation in hypoxia |
| Rebecca Gilchrist | Margaret R. Cunningham | Investigating the cellular complexity of drug-induced cardiotoxicity by fingerprinting single cell mass spectral information using Time-of-flight Secondary Ion Mass Spectrometry |
| Juma Akhtar | Ferran Valderrama | Investigating the effect of zona-occludens-1 in the stability of tight junction in prostate acini, and how this can contribute to the metastasis of prostate cancer |
| Katie Sharrocks | Mark Ashe | An investigation into the coregulation of glycolysis at the level of mRNA localisation by various signalling pathways |
| Hansa Shree | Chris Bakal | Endogenous DNA damage due to mechanical stress |
| Nikhil Harsiani | Frances Brodsky | Investigating the unique properties of the non-canonical isoform of clathrin |
| Anantha Krishnan S S | Margarete Heck | Using Drosophila to investigate gender-specific differences in the essential, conserved invadolysin metalloprotease |
| Flora Ka Kei Cheng | Jennifer Rohn | The role of the host cell cytoskeleton in cytoplasmic invasion by uropathogenic bacteria |
| Harry Pink | Helfrid Hochegger | Investigating the precise localisation, and mode of action of the Eg5 motor protein during centrosome separation by super-resolution microscopy |
| Matthew Bagley | Pier Paolo D’Avino | Localisation and function of PP1 phosphatases during cytokinesis |
Summer Studentships Funded 2017
| STUDENT | SUPERVISOR | PROJECT TITLE |
| Laura Hannett,University of Edinburgh | Nancy Papalopulu, University of Manchester | Absolute quantitative characterisation of transcription factor expression heterogeneity in breast cancer stem cells |
| Kenrick Dennis, Kings College London | Anne Ridley, Kings College London | Roles of PAK kinases in RhoH signalling |
| Evelyn Garlick, Durham University | Martin Goldberg, Durham University | Linking the cytoskeleton to the nuclear pore complex using super resolution light microscopy and correlative electron microscopy |
| Oğuz Kaan Yilmaz, University of Istanbul | Jordan Raff, University of Oxford | Dynamic investigation of centriole growth |
| Gabrielle Oxley, Durham University | Mary Herbert, Newcastle University | Harnessing the power of mitophagy to minimise the risk of transmitting mitochondrial DNA disease |
| Kate Murnane, University of York | Paul Pryor, University of York | The role of transcription factor SP6 in lysosome biogenesis |
| Laura Harrison, University of Bristol | David Stephens, University of Bristol | Imaging ER export of procollagen |
| Marius Cassidy, University of Manchester | Michelle Peckham, University of Leeds | Does Myo1e contribute to the metastatic phenotype of prostate cancer cells? |
| Frey Yann, University Paris Diderot (Paris VII) | Julie Welburn, University of Edinburgh | Mechanistic insights into MCAK regulation of microtubule length |
| Concepcion Garces Diaz, ETSIAM, Universitat Politecnica de Valencia | Stefan Marciniak, University of Cambridge | Elucidate the role of the GTPBP2 protein in stress granule dynamics, focussing on their disassembly upon recovery form stress |
| Ruth Ketley, University of Oxford | Justin Sturge, University of Hull | Development of an Endo180 fusion reporter protein using CRISPR/Cas9 gene editing in a model of pancreatic ductal adenocarcinoma to investigate how the hyperglycaemic microenvironment can enhance tumour progression |
| Alva Casey, Trinity College Dublin | James Murray, Trinity College Dublin | Involvement of autophagy machinery in microglial cell phagocytosis |
Summer Studentships Funded 2016
| STUDENT | SUPERVISOR | PROJECT TITLE |
| Vadim Demichev, University of Sheffield | Ewald Hettema, University of Sheffield | Is the myosin adaptor function of Pex19 evolutionarily conserved? |
| James Vines, University of Sheffield | Jason King, University of Sheffield | Catch me if you can: does BAR8 drive chemotaxis in Dictyostelium cells |
| Miriam Scarpa, University of Glasgow | Marisa Segal, University of Cambridge | CDK-dependent control of differential spindle pole fate in spindle morphogenesis |
| Yasmin Samir, University of Manchester | Mark Ashe, University of Manchester | Investigating the impact of mRNA modifications on localised actively translated glycolytic mRNAs |
| Oliver Inge, Imperial College, London | Chris Bakal, Institute of Cancer Research | The role of ARHGAP22 in the acquisition of Vemurafenib resistance |
| Kaylee Worlock, University of Exeter | Michael Deeks, University of Exeter | Live-cell imaging and modelling of phytopathogen-targeted secretion pathways |
| Hayley Smith, Nottingham University | Andrew Renault, Nottingham University | Germ Cell GPS – Determination of the molecular mechanisms guiding germ cells to the gonad |
| Sarah Adekola, National University of Ireland, Galway | Helen Dodson, National University of Ireland, Galway | Analysis of H2AX redistribution after DNA Damage using live cell fluorescence microscopy |
| Anna Dighero, University of Edinburgh | Masahiro Ono, Imperial College, London | To reveal the dynamic mechanism of Treg differentiation through TCR and costimulation signals in the thymus |
| Sonia Rolo, Catholic University of Lyon | Tobias Zech, University of Liverpool | Microtubule dynamics in hereditary spastic paraplegia type 8 |
Summer Studentships Funded 2015
| STUDENT | SUPERVISOR |
| Christian Bates, University of Manchester | Mark Ashe, University of Manchester |
| Callum Scotson, Aberystwyth University | John Doonan, Aberystwyth University |
| Rebecca Burge, University of Manchester | Catherine Lindon, University of Cambridge |
| Jessica Prince, Oxford University | Jonathon Pines, University of Cambridge |
| Jessica Upson, Oxford Brookes University | John Runions, Oxford Brookes University |
| Sophie Nock, University of Reading | Steve Thomas, University of Birmingham |
| Hannah Taylor-Lewis, University of Cambridge | Julie Welburn, University of Edinburgh |
| Daragh Elise Campbell, University of Glasgow | William Earnshaw, University of Edinburgh |
| Charlotte Guffick, University of York | Daniel Ungar, University of York |
| Rebecca Sharpe, University of Bristol | Jon Lane, University of Bristol |
| Yasmin Malde, University of Sussex | Helfrid Hochegger, University of Sussex |